N-Desbutyl bupivacaine-d6

N-Desbutyl bupivacaine-d6 (Desbutylbupivacaine-d6) is the deuterium labeled N-Desbutyl Bupivacaine (HY-W045132) . N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist[1][2].

Product Specifications

Product Name Alternative

Desbutylbupivacaine-d6

UNSPSC

12352005

Target

Drug Metabolite; Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Neurological Disease

Smiles

O=C(C1CCCCN1)NC2=C(C([2H])([2H])[2H])C=CC=C2C([2H])([2H])[2H]

Molecular Formula

C14H14D6N2O

Molecular Weight

238.36

References & Citations

[1]Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35 (2) :831-42.|[2]Alexander P Schwoerer, et al. A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels. Anesth Analg. 2015 Jun;120 (6) :1226-34.