N-Desbutyl Bupivacaine

N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist[1][2].

Product Specifications

CAS Number

[15883-20-2]

Product Name Alternative

Desbutylbupivacaine

UNSPSC

12352005

Hazard Statement

H301

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Purity

99.92

Smiles

CC1=CC=CC(C)=C1NC(C2CCCCN2)=O

Molecular Formula

C14H20N2O

Molecular Weight

232.32

Precautions

H301

References & Citations

[1]Meaghan A Paganelli, et al. Actions of Bupivacaine, a widely used local anesthetic, on NMDA receptor responses. J Neurosci. 2015 Jan 14;35 (2) :831-42.|[2]Alexander P Schwoerer, et al. A Comparative Analysis of Bupivacaine and Ropivacaine Effects on Human Cardiac SCN5A Channels. Anesth Analg. 2015 Jun;120 (6) :1226-34.