Dibenzosuberol
Dibenzosuberol (Compound 2) is a key intermediate in the synthesis of compounds associated with inhibiting Trypanosoma thiol reductase (TryR). Dibenzosuberol also shows inhibition of T. brucei with an EC50 value of 51.3 μM. Dibenzosuberol is also an impurity of Amitriptyline.
Product Specifications
CAS Number
1210-34-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Infection
Purity
99.84
Smiles
OC1C2=CC=CC=C2CCC3=CC=CC=C31
Molecular Formula
C15H14O
Molecular Weight
210.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Richardson JL, et al. Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis. ChemMedChem. 2009 Aug;4 (8) :1333-40.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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