Dibenzosuberol
Dibenzosuberol (Compound 2) is a key intermediate in the synthesis of compounds associated with inhibiting Trypanosoma thiol reductase (TryR) . Dibenzosuberol also shows inhibition of T. brucei with an EC50 value of 51.3 μM. Dibenzosuberol is also an impurity of Amitriptyline (HY-B0527) [1].
Product Specifications
CAS Number
[1210-34-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate; Parasite
Related Pathways
Anti-infection; Others
Field of Research
Infection
Purity
99.84
Smiles
OC1C2=CC=CC=C2CCC3=CC=CC=C31
Molecular Formula
C15H14O
Molecular Weight
210.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Richardson JL, et al. Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis. ChemMedChem. 2009 Aug;4 (8) :1333-40.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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