Xipamide-d6

Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1][2].

Product Specifications

CAS Number

[1330262-09-3]

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Solubility

10 mM in DMSO

Smiles

C(NC1=C(C([2H])([2H])[2H])C=CC=C1C([2H])([2H])[2H])(=O)C2=CC(S(N)(=O)=O)=C(Cl)C=C2O

Molecular Formula

C15H9D6ClN2O4S

Molecular Weight

360.85

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Prichard BN, et al. Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1985 Oct;30 (4) :313-32.|[3]Hannaert P, et al. Beneficial effects of xipamide on pH and Ca2+ ions of cardiac cells. Arch Mal Coeur Vaiss. 1990 Jul;83 (8) :1271-4.