5-Hydroxytryptophol (Standard)
5-Hydroxytryptophol is a mammalian serotonin metabolite that can be used as a sensitive biomarker for recent alcohol intake. 5-Hydroxytryptophol is formed by alcohol-induced changes in the serotonin metabolic pathway and is excreted in the urine as a glucuronic acid conjugate. 5-Hydroxytryptophol is elevated in urine excretion and can be used clinically to monitor alcohol intake in scenarios such as alcohol relapse[1][2].
Product Specifications
CAS Number
[154-02-9]
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
OC1=CC2=C(NC=C2CCO)C=C1
Molecular Formula
C10H11NO2
Molecular Weight
177.20
References & Citations
[1]Beck O, et al. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72.|[2]Eccleston D, et al. The formation of 5-hydroxytryptophol in brain in vitro. Br J Pharmacol Chemother. 1966 Dec;28 (3) :367-77.
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Scientific Category
Reference Standards
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