N-3-Hydroxydecanoyl-DL-homoserine lactone

N-3-Hydroxydecanoyl-DL-Homoserine lactone is a bacterial quorum-sensing molecule. N-3-Hydroxydecanoyl-DL-Homoserine lactone activates the transcription factor SdiA (EC50 = 0.6 µM), which detects N-acyl homoserine lactones (AHLs), and exerts its effect in Salmonella enterica (S. enterica) 12.

Product Specifications

CAS Number

[929222-14-0]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CCCCCCCC(CC(NC1C(OCC1)=O)=O)O

Molecular Formula

C14H25NO4

Molecular Weight

271.35

References & Citations

[1]Fekete A, et al. Identification of bacterial N-acylhomoserine lactones (AHLs) with a combination of ultra-performance liquid chromatography (UPLC), ultra-high-resolution mass spectrometry, and in-situ biosensors. Anal Bioanal Chem. 2007 Jan;387 (2) :455-67.|[2]Janssens JC, et al. Synthesis of N-acyl homoserine lactone analogues reveals strong activators of SdiA, the Salmonella enterica serovar Typhimurium LuxR homologue. Appl Environ Microbiol. 2007 Jan;73 (2) :535-44.