Butanoyl PAF

Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor (PAF) . Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold[1].

Product Specifications

CAS Number

[85405-03-4]

UNSPSC

12352211

Hazard Statement

H225-H319

Target

Platelet-activating Factor Receptor (PAFR)

Related Pathways

GPCR/G Protein

Field of Research

Metabolic Disease

Smiles

O=C(CCC)O[C@H](COCCCCCCCCCCCCCCCC)COP([O-])(OCC[N+](C)(C)C)=O

Molecular Formula

C28H58NO7P

Molecular Weight

551.74

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Davies SS, et al. Oxidized alkyl phospholipids are specific, high affinity peroxisome proliferator-activated receptor gamma ligands and agonists. J Biol Chem. 2001 May 11;276 (19) :16015-23.