DCAF15 ligand-1
DCAF15 ligand-1 (compound 9) is a ligand for the E3 ligase DCAF15. DCAF15 ligand-1 can be used in the synthesis of IBG1 (HY-153459) [1].
Product Specifications
CAS Number
[2098346-67-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.87
Smiles
O=S(C1=CC=C(CN)C=C1)(NC2=CC=C(C)C3=C2NC=C3C#N)=O
Molecular Formula
C17H16N4O2S
Molecular Weight
340.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Bussiere DE, et al. Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nat Chem Biol. 2020 Jan;16 (1) :15-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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