Chloraminophenamide

Chloraminophenamide (Compound 14) is a carbonic anhydrase inhibitor, with Kis of 75, 160 and 8400 nM for hCA II, bCA IV and hCA I, respectively. Chloraminophenamide has the potential for antiglaucoma research[1].

Product Specifications

CAS Number

[121-30-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Purity

99.79

Smiles

O=S(C1=C(Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O

Molecular Formula

C6H8ClN3O4S2

Molecular Weight

285.73

Precautions

H302, H315, H319, H335

References & Citations

[1]Scozzafava A, et, al. Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring? J Med Chem. 1999 Jul 15;42 (14) :2641-50.