Indole-3-pyruvic acid (Standard)

Indole-3-pyruvic acid (Standard) is the analytical standard of Indole-3-pyruvic acid. This product is intended for research and analytical applications. Indole-3-pyruvic acid, a keto analogue of tryptophan, is an orally active AHR agonist. Indole-3-pyruvic acid has antioxidant properties, and can be used in the research of inflammation, anxiety[1][2][3].

Product Specifications

CAS Number

[392-12-1]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Aryl Hydrocarbon Receptor; Endogenous Metabolite; Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Purity

99.38

Smiles

O=C(O)C(CC1=CNC2=CC=CC=C12)=O

Molecular Formula

C11H9NO3

Molecular Weight

203.20

Precautions

H315, H319, H335

References & Citations

[1]Reiji Aoki, et al. Indole-3-Pyruvic Acid, an Aryl Hydrocarbon Receptor Activator, Suppresses Experimental Colitis in Mice. J Immunol. 2018 Dec 15;201 (12) :3683-3693. |[2]Reiji Aoki, et al. Protective effect of indole-3-pyruvate against ultraviolet b-induced damage to cultured HaCaT keratinocytes and the skin of hairless mice. PLoS One. 2014 May 8;9 (5) :e96804. |[3]I P Lapin, et al. Anxiolytic effect of indole-3-pyruvic acid (IPA) in mice. Pharmacol Res. 1993 Sep;28 (2) :129-34.