Fluorene-d8
Fluorene-d8 is the deuterium labeled Fluorene. Fluorene is an orally active polycyclic aromatic hydrocarbon (PAH) and a precursor to other fluorene-based compounds. Fluorene and its derivatives serve as dye precursors for fluorene synthesis. In A549 cells, Fluorene induces oxidative stress and inflammatory responses by increasing ROS and SOD generation, exacerbating lipid peroxidation, modulating antioxidant enzyme activity, and upregulating the expression of pro-inflammatory factors TNF-α and IL-6. In vivo, Fluorene exhibits anxiolytic activity. Fluorene holds potential for research in inflammation and neurological disorders[1][2][3].
Product Specifications
CAS Number
35782-21-9
UNSPSC
12352005
Target
Fluorescent Dye; Interleukin Related; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS) ; SOD; TNF Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
[2H]C1=C2C3=C([2H])C([2H])=C([2H])C([2H])=C3CC2=C([2H])C([2H])=C1[2H]
Molecular Formula
C13H2D8
Molecular Weight
174.27
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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