IMB-XMA0038

IMB-XMA0038 is a MtASADH inhibitor with an IC50 value of 0.59 μg/mL. IMB-XMA0038 inhibits various agent-resistant Mycobacteria tuberculosis potently with MICs of 0.25-0.5 μg/mL. IMB-XMA0038 shows anti-tuberculosis activity[1].

Product Specifications

CAS Number

[921812-26-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Bacterial

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

[O-][N+](C1=CC=C(C(NC2=NN=C(C3OCCC3)O2)=O)O1)=O

Molecular Formula

C11H10N4O6

Molecular Weight

294.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wang X, et al. IMB-XMA0038, a new inhibitor targeting aspartate-semialdehyde dehydrogenase of Mycobacterium tuberculosis. Emerg Microbes Infect. 2021 Dec;10 (1) :2291-2299.