2-Aminotetralin

2-Aminotetralin is a potent and selective serotonin 5-HT1 agonist. 2-Aminotetralin exhibits high affinity (Ki≤25 nM) and at least 50-fold stereoselective preference at 5-HT1A, 5-HT1B, and 5-HT1D receptors[1].

Product Specifications

CAS Number

[2954-50-9]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Serotonin Transporter

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

NC1CC2=C(C=CC=C2)CC1

Molecular Formula

C10H13N

Molecular Weight

147.22

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]McGlynn RP, et, al. Development of 2-Aminotetralin-Type Serotonin 5-HT1 Agonists: Molecular Determinants for Selective Binding and Signaling at 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT1F Receptors. ACS Chem Neurosci. 2024 Jan 17;15 (2) :357-370.