Benzamidine (hydrochloride) (Standard)

Benzamidine hydrochloride is a trypsin-like serine proteases with Kis of 20, 21, 97, 110, 320 and 750 μM against Tryptase, Trypsin, uPA, Factor Xa, Thrombin and tPA, respectively[1].

Product Specifications

CAS Number

[1670-14-0]

UNSPSC

12352005

Target

Ser/Thr Protease

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

[H]Cl.N=C(C1=CC=CC=C1)N

Molecular Formula

C7H9ClN2

Molecular Weight

156.62

References & Citations

[1]Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7 (4) :299-312.|[2]J A Cairns, et al. Mast cell tryptase stimulates the synthesis of type I collagen in human lung fibroblasts. J Clin Invest. 1997 Mar 15;99 (6) :1313-21.