(R, R) -Traxoprodil

(R, R) -Traxoprodil is the the (R, R) -enantiomer of Traxoprodil (HY-W018061) . Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM[1].

Product Specifications

CAS Number

[134234-13-2]

Product Name Alternative

(R, R) -CP101,606

UNSPSC

12352005

Target

IGluR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

99.00

Smiles

OC1(CCN(CC1)[C@H](C)[C@H](O)C2=CC=C(C=C2)O)C3=CC=CC=C3

Molecular Formula

C20H25NO3

Molecular Weight

327.42

References & Citations

[1]Chenard BL, et al. (1S,2S) -1- (4-hydroxyphenyl) -2- (4-hydroxy-4-phenylpiperidino) -1-propanol: a potent new neuroprotectant which blocks N-methyl-D-aspartate responses. J Med Chem. 1995 Aug 4;38 (16) :3138-45.