4-Propylphenol

4-Propylphenol is a plant-derived phenolic compound. 4-Propylphenol causes an increase in ROS within the Fusarium graminearum cells, leading to damage to the DNA and cell membranes of the mycelia, effectively inhibiting the growth of the mycelia. 4-Propylphenol also has a growth inhibitory effect on walnut pathogenic fungi (C. gloeosporioides, C. siamense, A. alternata), with its EC50 ranging from 29.11 to 31.89 mg/L, and it also inhibits spore germination, with EC50 being 55.04-71.85 mg/L. 4-Propylphenol can be used in the research of fungal diseases in walnuts and wheat Fusarium head blight[1][2].

Product Specifications

CAS Number

[645-56-7]

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H318, H335, H412

Target

DNA/RNA Synthesis; Fungal; Reactive Oxygen Species (ROS)

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-anti-virus

Field of Research

Infection

Purity

99.87

Smiles

OC1=CC=C(C=C1)CCC

Molecular Formula

C9H12O

Molecular Weight

136.19

Precautions

H302+H312+H332, H315, H318, H335, H412

References & Citations

[1]Sun S, et al. Antifungal Activity and Mechanism of 4-Propylphenol Against Fusarium graminearum, Agent of Wheat Scab, and Its Potential Application. J Agric Food Chem. 2024 Mar 13;72 (10) :5258-5268.|[2]Yu X, et al. 4-Propylphenol Alters Membrane Integrity in Fungi Isolated from Walnut Anthracnose and Brown Spot. J Fungi (Basel) . 2025 Aug 22;11 (9) :610.