L-Pyrohomoglutamic acid
L-Pyrohomoglutamic acid is an amino acid building block. L-Pyrohomoglutamic acid can be used to synthesize ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors[1][2].
Product Specifications
CAS Number
34622-39-4
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents; Drug Intermediate
Related Pathways
Others
Field of Research
Others
Purity
97.91
Smiles
O=C([C@H](CCC1)NC1=O)O
Molecular Formula
C6H9NO3
Molecular Weight
143.14
Precautions
H315, H319, H335
References & Citations
[1]Pomplun S, et al. Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs) . Angew Chem Int Ed Engl. 2015 Jan 2;54 (1) :345-8. |[2]Taddei M, et al. Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors. Bioorg Med Chem Lett. 2014 Jan 1;24 (1) :61-4.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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