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L-Pyrohomoglutamic acid

L-Pyrohomoglutamic acid is an amino acid building block. L-Pyrohomoglutamic acid can be used to synthesize ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors[1][2].

Product Specifications

CAS Number

34622-39-4

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents; Drug Intermediate

Related Pathways

Others

Field of Research

Others

Purity

97.91

Smiles

O=C([C@H](CCC1)NC1=O)O

Molecular Formula

C6H9NO3

Molecular Weight

143.14

Precautions

H315, H319, H335

References & Citations

[1]Pomplun S, et al. Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs) . Angew Chem Int Ed Engl. 2015 Jan 2;54 (1) :345-8. |[2]Taddei M, et al. Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors. Bioorg Med Chem Lett. 2014 Jan 1;24 (1) :61-4.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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