Homogentisic acid lactone

Homogentisic acid lactone (Compound 1) is a fungal metabolite with fungicidal activity, which is found in the fungus WF5. Homogentisic acid lactone is active against the plant pathogenic fungus F. graminearum. Homogentisic acid lactone can be used as a substrate in the determination of serum paraoxonase/arylesterase 1 (PON1) activity[1][2].

Product Specifications

CAS Number

[2688-48-4]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Fungal

Related Pathways

Anti-infection

Field of Research

Infection

Purity

99.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C(O2)C(CC2=O)=C1

Molecular Formula

C8H6O3

Molecular Weight

150.13

Precautions

H315, H319, H335

References & Citations

[1]Mousa WK, et al. Characterization of Antifungal Natural Products Isolated from Endophytic Fungi of Finger Millet (Eleusine coracana) . Molecules. 2016 Sep 3;21 (9) :1171. |[2]Bełtowski J, et al. Leptin decreases plasma paraoxonase 1 (PON1) activity and induces oxidative stress: the possible novel mechanism for proatherogenic effect of chronic hyperleptinemia. Atherosclerosis. 2003 Sep;170 (1) :21-9.