L-Cysteinesulfinic acid (monohydrate) (Standard)

L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively[1].

Product Specifications

CAS Number

[207121-48-0]

UNSPSC

12352211

Target

Endogenous Metabolite; mGluR

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

N[C@@H](CS(O)=O)C(O)=O.O

Molecular Formula

C3H9NO5S

Molecular Weight

171.17

References & Citations

[1]Shi Q, et al. L-homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists. J Pharmacol Exp Ther. 2003 Apr;305 (1) :131-42.|[2]Boss V, et al. L-cysteine sulfinic acid as an endogenous agonist of a novel metabotropic receptor coupled to stimulation of phospholipase D activity.