CFL-137 (Standard)

CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].

Product Specifications

CAS Number

[708-06-5]

UNSPSC

12352005

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Smiles

O=CC1=C2C=CC=CC2=CC=C1O

Molecular Formula

C11H8O2

Molecular Weight

172.18

References & Citations

[1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TRC-D235185-25MG 25 mg

3-(2-Deoxy-b-D-erythro-pentofuranosyl)-3,5-dihydropyrimido[1,2-a]purine-6,10-dione

Ask

View Details

MBS3203278-01 0.1 mL

ALX4 antibody - C-terminal region

Ask

View Details

MBS3203278-02 5x 0.1 mL

ALX4 antibody - C-terminal region

Ask

View Details

PVT67036 2 µg

PCMV-EGFP-PRSS8-FLAG-Neo Plasmid

Ask

View Details

129555-ML490 100 µL

MEF2A (Myocyte-specific Enhancer Factor 2A, Serum Response Factor-like Protein 1, MEF2) (MaxLight 490)

Ask

View Details

MBS8223732-01 15 nmol

HOOK3 siRNA (Mouse)

Ask

View Details