CFL-137 (Standard)
CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].
Product Specifications
CAS Number
[708-06-5]
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Smiles
O=CC1=C2C=CC=CC2=CC=C1O
Molecular Formula
C11H8O2
Molecular Weight
172.18
References & Citations
[1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.
Shipping Conditions
Room temperature
Scientific Category
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