CFL-137 (Standard)
CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].
Product Specifications
CAS Number
[708-06-5]
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Smiles
O=CC1=C2C=CC=CC2=CC=C1O
Molecular Formula
C11H8O2
Molecular Weight
172.18
References & Citations
[1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1453949-01 0.02 mg (E-Coli)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details 
MBS1453949-02 0.1 mg (E-Coli)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details 
MBS1453949-03 0.02 mg (Yeast)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details MBS1453949-04 0.1 mg (Yeast)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details MBS1453949-05 0.02 mg (Baculovirus)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details MBS1453949-06 0.02 mg (Mammalian-Cell)
Recombinant Staphylococcus aureus 7-cyano-7-deazaguanine synthase (queC)
Ask
View Details