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CFL-137 (Standard)

CFL-137 is a potent KRasG12C inhibitor. CFL-137 shows an antiproliferative effect. CFL-137 shows anticancer activity. CFL-137 has the potential for the research of lung cancer[1].

Product Specifications

CAS Number

708-06-5

UNSPSC

12352005

Target

Ras

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Field of Research

Cancer

Smiles

O=CC1=C2C=CC=CC2=CC=C1O

Molecular Formula

C11H8O2

Molecular Weight

172.18

References & Citations

[1]Orgován Z, et al. Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency. Eur J Med Chem. 2023 Mar 15;250:115212.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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