4-Diethylaminobenzaldehyde (Standard)

4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM) [1][2].

Product Specifications

CAS Number

[120-21-8]

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=CC1=CC=C(N(CC)CC)C=C1

Molecular Formula

C11H15NO

Molecular Weight

177.25

References & Citations

[1]Luo M, et al. Diethylaminobenzaldehyde is a covalent, irreversible inactivator of ALDH7A1. ACS Chem Biol. 2015 Mar 20;10 (3) :693-7.|[2]Araki N, et al. Screening for androgen receptor activities in 253 industrial chemicals by in vitro reporter gene assays using AR-EcoScreen cells. Toxicol In Vitro. 2005 Sep;19 (6) :831-42.