Acivicin (Standard)

Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway[1][2][3].

Product Specifications

CAS Number

[42228-92-2]

Product Name Alternative

AT-125 (Standard) ; U-42126 (Standard)

UNSPSC

12352005

Target

Parasite; Reference Standards; γ-Glutamyl Transferase (GGT)

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection

Smiles

ClC1=NO[C@@]([C@H](N)C(O)=O)([H])C1

Molecular Formula

C5H7ClN2O3

Molecular Weight

178.57

References & Citations

[1]Kreuzer J, et al. Target discovery of acivicin in cancer cells elucidates its mechanism of growth inhibition. Chem Sci. 2014 Dec 1;6 (1) :237-245. Epub 2014 Sep 26.|[2]Chikhale EG, et al. Carrier-mediated transport of the antitumor agent acivicin across the blood-brain barrier. Biochem Pharmacol. 1995 Mar 30;49 (7) :941-5.|[3]Delphine Waniusiow, et al. Toluene-induced hearing loss in acivicin-treated rats. Neurotoxicol Teratol. May-Jun 2008;30 (3) :154-60.