Ompenaclid (Standard)
Ompenaclid (RGX-202) is an oral small-molecule SLC6A8 transporter inhibitor. Ompenaclid robustly inhibits creatine import in vitro and in vivo, reduces intracellular phosphocreatine and ATP levels, and induces tumor apoptosis. Ompenaclid can be used for the research of cancer and duchenne muscular dystrophy[1][2].
Product Specifications
CAS Number
353-09-3
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(O)CCNC(N)=N
Molecular Formula
C4H9N3O2
Molecular Weight
131.14
References & Citations
[1]Kurth I, et al. Therapeutic targeting of SLC6A8 creatine transporter suppresses colon cancer progression and modulates human creatine levels. Sci Adv. 2021 Oct 8;7 (41) :eabi7511.|[2]Creisméas A, et, al. TRPC1 and TRPC3 involvement in DMD physiopathology and as potential targets for treatment in complement to rAAV-microdystrophin. 2021 Oct 1;13.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB2784-500 1x 500 µL
AKT1 (Prognostic Marker for Neuroendocrine Tumors) (AKT1/2784), 0.2mg/mL
Sign In for Pricing
View Details 
BNC680210-500 1x 500 µL
Giardia lamblia (BB1.1E5), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BPTL-269 1 Unit
Liquid Petroleum Products Hydrocarbon Types Tester BPTL-269
Sign In for Pricing
View Details 
BNC471730-100 1x 100 µL
MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNUB1815-100 1x 100 µL
Chromogranin A / CHGA (Neuroendocrine Marker) (CHGA/1815R), 0.2mg/mL
Sign In for Pricing
View Details 
BNUB2052-100 1x 100 µL
TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), 0.2mg/mL
Sign In for Pricing
View Details