3-Methylquinoline
3-Methylquinoline is a selective cytochrome P450 (CYP1A2) inhibitor with an IC50 of 13 μM. 3-Methylquinoline can reduce the metabolic clearance of CYP1A2 substrate drugs. 3-Methylquinoline can inhibit the activation of carcinogenic precursors[1].
Product Specifications
CAS Number
[612-58-8]
UNSPSC
12352005
Hazard Statement
H312+H332, H315, H318, H335, H351
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease
Purity
98.83
Smiles
CC1=CN=C2C=CC=CC2=C1
Molecular Formula
C10H9N
Molecular Weight
143.19
Precautions
H312+H332, H315, H318, H335, H351
References & Citations
[1]Korhonen LE, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48 (11) :3808-15.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
CYP1
Available Sizes
Curated Selection
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