LANA-IN-1

LANA-IN-1 (compound 8) is an N-acetyl-derived LANA inhibitor with antiviral activity against herpesvirus. In fluorescence assays using the LANA probe LBS2, 1 mM LANA-IN-1 shows an inhibition rate of 32%. LANA-IN-1 may inhibit the interaction between LANA and the viral genome[1].

Product Specifications

CAS Number

[2221-00-3]

Product Name Alternative

4- (1H-Imidazol-1-yl) aniline

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

HSV

Related Pathways

Anti-infection

Field of Research

Infection

Purity

99.89

Smiles

NC(C=C1)=CC=C1N2C=CN=C2

Molecular Formula

C9H9N3

Molecular Weight

159.19

Precautions

H315, H319, H335

References & Citations

[1]Kirsch P, et al. Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8. J Med Chem. 2019 Apr 25;62 (8) :3924-3939.