D-Ala-D-Ala (Standard)

D-Ala-D-Ala (Standard) is the analytical standard of D-Ala-D-Ala. This product is intended for research and analytical applications. D-Ala-D-Ala is a bacterial endogenous metabolite. D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase[1][2][3].

Product Specifications

CAS Number

[923-16-0]

Product Name Alternative

D-Alanyl-D-alanine (Standard) ; H-D-Ala-D-Ala-OH (Standard)

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

C[C@H](C(O)=O)NC([C@@H](C)N)=O

Molecular Formula

C6H12N2O3

Molecular Weight

160.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65 (Pt 10) :1098-106.|[2]Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16 (20) :2566-80.