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1,5-Isoquinolinediol (Standard)

1,5-Isoquinolinediol is a potent PARP inhibitor, with an IC50 of 0.18-0.37 μM. 1,5-Isoquinolinediol attenuates diabetes-induced NADPH oxidase-derived oxidative stress in retina[1][2].

Product Specifications

CAS Number

5154-02-9

UNSPSC

12352005

Target

PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Metabolic Disease

Smiles

O=C1NC=CC2=C1C=CC=C2O

Molecular Formula

C9H7NO2

Molecular Weight

161.16

References & Citations

[1]Crockett SL, et al. Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness. Pediatr Res. 2019 Dec 9.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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