1,5-Isoquinolinediol (Standard)
1,5-Isoquinolinediol is a potent PARP inhibitor, with an IC50 of 0.18-0.37 μM. 1,5-Isoquinolinediol attenuates diabetes-induced NADPH oxidase-derived oxidative stress in retina[1][2].
Product Specifications
CAS Number
[5154-02-9]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Metabolic Disease
Smiles
O=C1NC=CC2=C1C=CC=C2O
Molecular Formula
C9H7NO2
Molecular Weight
161.16
References & Citations
[1]Crockett SL, et al. Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness. Pediatr Res. 2019 Dec 9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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