1-Anthramine
1-Anthramine (1-aminoanthracene) is a fluorescent general anesthetic. potentiates GABAergic transmission with Kd = 0.1 mM, for binding to the general anesthetic site in horse spleen apoferritin (HSAF) . 1-Anthramine fluorescence is enhanced when bound to HSAF. 1-Anthramine potentiates chloride currents elicited by GABA. 1-Anthramine can reversibly inhibit the movement of Xenopus laevis, with an EC50 value of 16 μM[1].
Product Specifications
CAS Number
610-49-1
Product Name Alternative
1-Aminoanthracene
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Chloride Channel; Fluorescent Dye; GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
98.41
Smiles
NC1=CC=CC2=CC3=C(C=C12)C=CC=C3
Molecular Formula
C14H11N
Molecular Weight
193.24
Precautions
H315, H319, H335
References & Citations
[1]Butts CA, et al. Identification of a fluorescent general anesthetic, 1-aminoanthracene. Proc Natl Acad Sci U S A. 2009 Apr 21;106 (16) :6501-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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