1,12-Dodecanediamine
1,12-Dodecanediamine (1,12-DD) is a reversible Maxi calcium-activated potassium channel blocker. 1,12-Dodecanediamine can reduce the single-channel current amplitude, mean channel open time, and channel open probability. 1,12-Dodecanediamine is promising for research of cell electrical signal transduction mechanism[1].
Product Specifications
CAS Number
[2783-17-7]
Product Name Alternative
1,12-DD; 1,12-Diamino dodecane
UNSPSC
12352211
Hazard Statement
H302, H314, H317
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Purity
99.44
Smiles
NCCCCCCCCCCCCN
Molecular Formula
C12H28N2
Molecular Weight
200.36
Precautions
H302, H314, H317
References & Citations
[1]Weiger TM, et al. External action of di- and polyamines on maxi calcium-activated potassium channels: an electrophysiological and molecular modeling study. Biophys J. 1998 Feb;74 (2 Pt 1) :722-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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