2,6-Dichlorophenylacetic acid

2,6-Dichlorophenylacetic acid is an inhibitor of isopenicillin N synthase (IPNS) and acyl-CoA: 6-APA acyltransferase. 2,6-Dichlorophenylacetic acid is also part of a group of phenylacetate derivatives that have cytostatic activity against tumour cells[1][2].

Product Specifications

CAS Number

[6575-24-2]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Acyltransferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Purity

99.97

Smiles

ClC(C=CC=C1Cl)=C1CC(O)=O

Molecular Formula

C8H6Cl2O2

Molecular Weight

205.04

Precautions

H315, H319

References & Citations

[1]Zhu Y, et al. Synthesis, structures and urease inhibitory activities of three silver (I) complexes derived from 2, 6-dichlorophenylacetic acid[J]. Inorganica Chimica Acta, 2019, 484: 42-46.|[2]Tsukagoshi K, et al. Steric hindrance of 2,6-disubstituted benzoic acid derivatives on the uptake via monocarboxylic acid transporters from the apical membranes of Caco-2 cells. Pestic Biochem Physiol. 2014 May;111:38-42.