TRPM8 agonist WS-3 (Standard)
TRPM8 agonist WS-3 (Standard) is the analytical standard of TRPM8 agonist WS-3. This product is intended for research and analytical applications. TRPM8 agonist WS-3 is an specific agonist of TRPM8 with an EC50 of 3.7 μM. TRPM8 agonist WS-3 inhibits epileptic seizures through a TRPM8 dependent mechanism. TRPM8 agonist WS-3 can be used for research on epilepsy and other conditions[1][2].
Product Specifications
CAS Number
39711-79-0
Product Name Alternative
Framidice 3 (Standard)
UNSPSC
12352211
Target
Endogenous Metabolite; Reference Standards; TRP Channel
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Smiles
CC(C)C1CCC(C)CC1C(NCC)=O
Molecular Formula
C13H25NO
Molecular Weight
211.35
References & Citations
[1]Behrendt HJ, et al. Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141 (4) :737-45.|[2]Moriyama H, et al. Anti-seizure effects of WS-3, a TRPM8 agonist, on focal onset seizure mouse model via reduction of extracellular glutamate levels. Neuropsychopharmacology. 2025 Nov;50 (12) :1855-1863.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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