Calcium 2-oxoglutarate (Standard)

Calcium 2-oxoglutarate (Standard) is the analytical standard of Calcium 2-oxoglutarate (HY-W013636B) . This product is intended for research and analytical applications. Calcium 2-oxoglutarate is an intermediate in the production of ATP or GTP in the Krebs cycle. Calcium 2-oxoglutarate also acts as the major carbon skeleton for nitrogen-assimilatory reactions. Calcium 2-oxoglutarate is a reversible inhibitor of tyrosinase (IC50=15 mM) [1][2].

Product Specifications

CAS Number

[71686-01-6]

Target

Endogenous Metabolite; Reference Standards; Tyrosinase

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C([O-])C(CCC([O-])=O)=O.[Ca+2]

Molecular Formula

C5H4CaO5

Molecular Weight

184.16

References & Citations

[1]Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79 (4) :419-35.|[2]Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105 (Pt 3) :1654-1662.