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7,8-Dihydroxyflavone (Standard)

7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF) . Displays therapeutic efficacy toward various neurological diseases[1].

Product Specifications

CAS Number

38183-03-8

UNSPSC

12352005

Target

Apoptosis; Trk Receptor

Related Pathways

Apoptosis; Neuronal Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Neurological Disease

Smiles

O=C1C=C(C2=CC=CC=C2)OC3=C(O)C(O)=CC=C13

Molecular Formula

C15H10O4

Molecular Weight

254.24

References & Citations

[1]Zhang Z, et al. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology. 2014 Feb;39 (3) :638-50.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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