2-Methylthiophenothiazine
2-Methylthiophenothiazine (compound 17) is a precursor of tubulin inhibitor with potential anticancer activity and can inhibit tubulin aggregation[1][2].
Product Specifications
CAS Number
[7643-08-5]
UNSPSC
12352005
Hazard Statement
H302, H317, H373, H410
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Purity
99.77
Smiles
CSC1=CC(NC2=CC=CC=C2S3)=C3C=C1
Molecular Formula
C13H11NS2
Molecular Weight
245.36
Precautions
H302, H317, H373, H410
References & Citations
[1]Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54 (12) :4247-63.|[2]Glass-Marmor L, et al. Calmodulin antagonists decrease glucose 1,6-bisphosphate, fructose 1,6-bisphosphate, ATP and viability of melanoma cells. Eur J Pharmacol. 1996 Oct 17;313 (3) :265-71.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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