7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
Selected Variant
HY-W011640-01
Size: 25 mg
7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters[1], which are capable of forming covalent DNA adducts and inducing mutations[2].
Product Specifications
CAS Number
6272-55-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Biochemical Assay Reagents
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
98.09
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
OC1CCCC2=C3C=CC4=CC=CC5=C4C3=C(C=C21)C=C5
Molecular Formula
C20H16O
Molecular Weight
272.35
Precautions
H302, H315, H319, H332, H335
References & Citations
[1]Glatt H, Pauly K, Frank H, Seidel A, Oesch F, Harvey RG, Werle-Schneider G. Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat. Carcinogenesis. 1994 Nov;15 (11) :2605-11.|[2]Surh YJ, Tannenbaum SR. Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene. Chem Res Toxicol. 1995 Jul-Aug;8 (5) :693-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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