Dihexyl phthalate

Dihexyl phthalate is one of the commonly used phthalate esters in various plastics and consumer products. Dihexyl phthalate is classified as a priority pollutant and an endocrine disruptor. Dihexyl phthalate can induce reactive oxygen species (ROS) accumulation, promote inflammation, and lead to significant increases in apoptosis and inflammation-related gene expression levels. Dihexyl phthalate can cause testicular atrophy and is a reproductive toxicant[1][2].

Product Specifications

CAS Number

[84-75-3]

UNSPSC

12352005

Hazard Statement

H360

Target

Apoptosis; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Purity

98.0

Smiles

O=C(OCCCCCC)C1=CC=CC=C1C(OCCCCCC)=O

Molecular Formula

C20H30O4

Molecular Weight

334.46

Precautions

H360

References & Citations

[1]Kim YH, et al. Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase. J Appl Microbiol. 2007 Jan;102 (1) :221-8.|[2]Song D, et al. Combining metabolomics with bioanalysis methods to investigate the potential toxicity of dihexyl phthalate[J]. Environmental toxicology, 2021, 36 (2) : 213-222.