Isoxazole (Standard)

Amfenac (Sodium Hydrate) (Standard) is the analytical standard of Amfenac (Sodium Hydrate) . This product is intended for research and analytical applications. Amfenac Sodium Hydrate is a COX-2 inhibitor.

Product Specifications

CAS Number

[288-14-2]

UNSPSC

12352005

Target

Antibiotic; ATP-binding cassette (ABC) transporters; Bacterial; Epigenetic Reader Domain; Fungal; HSP; Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Epigenetics; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Smiles

C1=CON=C1

Molecular Formula

C3H3NO

Molecular Weight

69.06

References & Citations

[1]Zhu J, et al. The recent progress of isoxazole in medicinal chemistry. Bioorg Med Chem. 2018 Jul 23;26 (12) :3065-3075. |[2]Sysak A, et al. Isoxazole ring as a useful scaffold in a search for new therapeutic agents. Eur J Med Chem. 2017 Sep 8;137:292-309. |[3]Norman BH, et al. Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1) [J]. Bioorg Med Chem Lett. 2002 Mar 25;12 (6) :883-6.|[4]Agrawal N, Mishra P. The synthetic and therapeutic expedition of isoxazole and its analogs[J]. Med Chem Res. 2018;27 (5) :1309-1344.|[5]Kalwat MA, et al. Isoxazole Alters Metabolites and Gene Expression, Decreasing Proliferation and Promoting a Neuroendocrine Phenotype in β-Cells. ACS Chem Biol. 2016 Apr 15;11 (4) :1128-36.