L-Homocysteine (Standard)

L-Homocysteine (Standard) is the analytical standard of L-Homocysteine. This product is intended for research and analytical applications. L-Homocysteine, an amino acid, is a homocysteine that has L configuration. Homocysteine is an essential intermediate in normal mammalian metabolism of methionine. L-Homocysteine induces upregulation of Cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2].

Product Specifications

CAS Number

[6027-13-0]

UNSPSC

12352211

Hazard Statement

H302

Target

Cathepsin; Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Purity

98.83

Smiles

N[C@@H](CCS)C(O)=O

Molecular Formula

C4H9NO2S

Molecular Weight

135.19

Precautions

P264-P270-P330-P501

References & Citations

[1]Finkelstein JD, et al. Homocysteine. Int J Biochem Cell Biol. 2000 Apr;32 (4) :385-9.|[2]Leng YP, et al. l-Homocysteine-induced cathepsin V mediates the vascular endothelial inflammation in hyperhomocysteinaemia. Br J Pharmacol. 2018 Apr;175 (8) :1157-1172.