2,6-Dimethylquinoline (Standard)
2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 µM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 µM[1][2][3].
Product Specifications
CAS Number
877-43-0
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
CC1=CC2=C(C=C1)N=C(C)C=C2
Molecular Formula
C11H11N
Molecular Weight
157.22
References & Citations
[1]Laura E Korhonen, et al. Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors. J Med Chem. 2005 Jun 2;48 (11) :3808-15.|[2]L E Korhonen, et al. New potent and selective cytochrome P450 2B6 (CYP2B6) inhibitors based on three-dimensional quantitative structure-activity relationship (3D-QSAR) analysis. Br J Pharmacol. 2007 Apr;150 (7) :932-42.|[3]Cun Zhang, et al. Studies on chemical constituents from roots of Peucedanum praeruptorum II. Zhongguo Zhong Yao Za Zhi. 2006 Aug;31 (16) :1333-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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