4-Hydroxyphenylpyruvic acid (Standard)

4-Hydroxyphenylpyruvic acid (Standard) is the analytical standard of 4-Hydroxyphenylpyruvic acid (HY-W010040) . This product is intended for research and analytical applications. 4-Hydroxyphenylpyruvic acid is an intermediate in the metabolism of the amino acid phenylalanine. 4-Hydroxyphenylpyruvic acid is a substrate of 4-hydroxyphenylpyruvic acid dioxygenase. 4-Hydroxyphenylpyruvic acid can be used in the study of HPD-related diseases, such as type III tyrosinemia and hawkinsinuria[1][2].

Product Specifications

CAS Number

[156-39-8]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Endogenous Metabolite; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Purity

96.44

Smiles

O=C(O)C(CC1=CC=C(O)C=C1)=O

Molecular Formula

C9H8O4

Molecular Weight

180.16

Precautions

H315, H319

References & Citations

[1]Brand LM, et al. Effect of glucagon on phenylalanine metabolism and phenylalanine-degrading enzymes in the rat. Biochem J. 1974 Aug;142 (2) :231-45.|[2]Tomoeda K, et al. Mutations in the 4-hydroxyphenylpyruvic acid dioxygenase gene are responsible for tyrosinemia type III and hawkinsinuria. Mol Genet Metab. 2000 Nov;71 (3) :506-10.