Meso-Tetra (4-pyridyl) porphine
Selected Variant
HY-W008874-01
Size: 250 mg
Meso-Tetra (4-pyridyl) porphine (Compound 10) is a porphyrin derivative. meso-Tetra (4-pyridyl) porphine is a weak inhibitor of human topoisomerase I (Top1) with an EC50 value greater than 50 µM. meso-Tetra (4-pyridyl) porphine can be used in tumor research[1].
Product Specifications
CAS Number
16834-13-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
97.0
Smiles
C1(/C2=CC=NC=C2)=C3C=CC(/C(C4=CC=NC=C4)=C5C=C/C(N/5)=C(C6=CC=NC=C6)/C(C=C/7)=NC7=C(C8=CC=NC=C8)/C9=CC=C1N9)=N/3
Molecular Formula
C40H26N8
Molecular Weight
618.70
Precautions
H302, H315, H319, H335
References & Citations
[1]Das SK, et al. Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes. J Med Chem. 2018 Feb 8;61 (3) :804-817.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
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