2-Bromo-4'-fluoroacetophenone

2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

Product Specifications

CAS Number

403-29-2

Product Name Alternative

P-Fluorophenacyl bromide

UNSPSC

12352005

Hazard Statement

H314

Target

DNA/RNA Synthesis

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

99.29

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

BrCC(C1=CC=C(F)C=C1)=O

Molecular Formula

C8H6BrFO

Molecular Weight

217.04

Precautions

H314

References & Citations

[1]Wender P A, et al. Photoinduced cleavage of DNA by bromofluoroacetophenone–pyrrolecarboxamide conjugates[J]. Bioorganic & medicinal chemistry letters, 2003, 13 (10) : 1763-1766.