Diphenyl Phosphate (Standard)

Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases[1][2].

Product Specifications

CAS Number

[838-85-7]

UNSPSC

12352005

Target

Mitochondrial Metabolism

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=P(OC1=CC=CC=C1)(OC2=CC=CC=C2)O

Molecular Formula

C12H11O4P

Molecular Weight

250.19

References & Citations

[1]Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55 (19) :13122-13131. |[2]Wang D, et al. Neonatal triphenyl phosphate and its metabolite diphenyl phosphate exposure induce sex- and dose-dependent metabolic disruptions in adult mice. Environ Pollut. 2018 Jun;237:10-17.