Diphenyl Phosphate (Standard)
Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases[1][2].
Product Specifications
CAS Number
838-85-7
UNSPSC
12352005
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=P(OC1=CC=CC=C1)(OC2=CC=CC=C2)O
Molecular Formula
C12H11O4P
Molecular Weight
250.19
References & Citations
[1]Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55 (19) :13122-13131. |[2]Wang D, et al. Neonatal triphenyl phosphate and its metabolite diphenyl phosphate exposure induce sex- and dose-dependent metabolic disruptions in adult mice. Environ Pollut. 2018 Jun;237:10-17.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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