Acetobromo-a-D-glucuronic acid-13C6 methyl ester

Acetobromo-a-D-glucuronic acid-13C6 methyl ester (Methyl acetobromo-α-D-glucuronate-13C6 methyl ester) is 13C labeled Acetobromo-α-D-glucuronic acid methyl ester, 98% (HY-W008125) . Acetobromo-α-D-glucuronic acid methyl ester, 98% is an intermediate. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used to synthesize HMR1098-S-Glucuronide Methyl Ester. HMR1098 is a novel KATP blocker that is metabolized to S-glucuronide in rat and dog bile. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used in the research of sudden cardiac death[1][2].

Product Specifications

Product Name Alternative

Methyl acetobromo-α-D-glucuronate-13C6 methyl ester

UNSPSC

12352211

Target

Biochemical Assay Reagents; Drug Intermediate; Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Cardiovascular Disease

Smiles

CC(O[13C@H]1[13C@@H]([C@H](O[13C@@H]([13C@@H]1OC(C)=O)Br)[13C](O[13CH3])=O)OC(C)=O)=O

Molecular Formula

C7 13C6H17BrO9

Molecular Weight

403.13

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Ethell BT, et al. Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides. Drug Metab Dispos. 2003 Aug;31 (8) :1027-34.