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2-Aminoquinoline (Standard)

2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1][2].

Product Specifications

CAS Number

580-22-3

UNSPSC

12352005

Target

NO Synthase; Orthopoxvirus

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection; Neurological Disease

Smiles

NC1=NC2=CC=CC=C2C=C1

Molecular Formula

C9H8N2

Molecular Weight

144.18

References & Citations

[1]Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60 (16) :7146-7165.|[2]Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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